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Filtering by: Subject RNA viruses Committee Member Braunworth, Bill

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:

Chiu, Wei-Wei

Abstract:

In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...

Resource Type:

Dissertation

Full Text:

1, 2001. Title: Translation of Dengue Virus RNA: Influence of the Untranslated Regions on 5´- cap