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Filtering by: Advisor Chappell, Patrick Committee Member Buermeyer, Andrew

Effect of PFAS Exposure on Reproduction : a Comparative Investigation between Kisspeptin-secreting AVPV and Arcuate Nuclei

Creator:

Jacobs, Dakota

Abstract:

Ovulation requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from preoptic hypothalamic neurons, initiated by elevated ovarian estradiol (E₂). Rising estradiol activates a subset of sexually dimorphic kisspeptin (Kiss-1) neurons in the female, located in the anteroventral periventricular nuclei (AVPV). Conversely, estradiol negative feedback on GnRH secretion is mediated by a...

Resource Type:

Masters Thesis

Full Text:

: ______________________________________________________ Patrick E. Chappell Ovulation requires preovulatory surges of gonadotropin-releasing
Probing Circadian Clock-Steroid Receptor Interactions in GnRH Neurons

Creator:

Grimwood, Victoria J.

Abstract:

Endogenous circadian clock regulation is essential to normal rhythmicity, particularly the timing of hormone release in the brain. In the context of mammalian reproduction, a surge of a specific hormone, gonadotrophin-releasing hormone (GnRH), initiates a surge of luteinizing hormone (LH) from the pituitary gland, which is required for ovulation in...

Resource Type:

Honors College Thesis