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Filtering by: Subject Methemoglobinemia Committee Member Buhler, Donald

An assessment of the cardiac toxicity of compounds that cause methemoglobinemia using a non-vascularized fish heart model

Creator:

Nichols, John W.

Abstract:

Non-vascularized hearts of buffalo sculpin (Enophrys bison) were used to investigate the cardiac toxicity of compounds that cause methemoglobinemia. The affinity of sculpin cardiac myoglobin for oxygen (P50 = 1.10 torr at 20 C°, pH 7.8) was lower than that of mammals studied (P50 = .44 and .76 torr for...

Resource Type:

Dissertation

Full Text:

cause methemoglobinemia using a non-vascularized fish heart model AN ABSTRACT OF THE THESIS OF John