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Cooperation and conflict in Pseudomonas aeruginosa quorum sensing

Creator:: Wilder, Cara N.
Abstract:: Pseudomonas aeruginosa is an environmental bacterium as well as an opportunistic pathogen that primarily infects immunocompromised individuals, including those suffering from cystic fibrosis. The density-dependent regulation of gene expression via cell-to-cell communication, also termed quorum sensing (QS), is an important virulence determinant in this organism. Generally, P. aeruginosa uses three...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Cara N. Wilder for

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

Creator:: Asfahl, Kyle L.
Abstract:: Cell-cell communication in bacteria is understood to facilitate the coordination of population-wide cooperative behavior in the form of concerted gene expression. The opportunistic pathogen Pseudomonas aeruginosa uses such a communication mechanism to regulate a large group of genes important to virulence strategies in this bacterium. This general mechanism of communication...
Resource Type:: Dissertation
Full Text:: . aeruginosa, like many Gram-negative Proteobacteria, is mediated through the synthesis of diffusible N-acyl

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Creator:: Sexton, David
Abstract:: Cooperative behaviors in bacteria are increasingly appreciated for their relevance to microbial ecology and utility as model systems for social evolution. One example is the secretion of siderophores, a structurally diverse group of compounds that chelate extracellular iron. Siderophore production is considered cooperative because the benefits can be shared with...
Resource Type:: Dissertation
Full Text:: -dependent mechanism (Noinaj et al., 2010). 6 FpvA interacts with TonB through a conserved N

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Creator:: Mellbye, Brett L.
Abstract:: Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
Resource Type:: Dissertation
Full Text:: a signal synthase, LasI, that synthesizes N-3-oxo-dodecanoyl-homoserine lactone (3OC12-HSL), and a

Evolution of a streamlined cooperator in Pseudomonas aeruginosa quorum sensing

Creator:: Huie, Jessica L.
Abstract:: Social behavior leading to the production of common goods is prone to exploitation. One such behavior in Pseudomonas aeruginosa is quorum sensing (QS), by which the bacteria produce signals to regulate extracellular common goods. Exploitation comes in the form of cheaters which have a mutation in the central quorum sensing...
Resource Type:: Masters Thesis
Full Text:: LuxR-type autoinducer synthases LasI and RhlI produce N-3- oxododecanoyl-HSL (3OC12-HSL) and N-butyryl

Quorum sensing gene regulation in Pseudomonas aeruginosa

Creator:: Gupta, Rashmi
Abstract:: Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
Resource Type:: Dissertation
Full Text:: , 1985). The LuxR protein contains two functional domains. The N-terminal domain interacts with the

The proteomic and transcriptomic responses to iron, sulfur, and nitrogen limitation in the abundant marine bacterium Candidatus Pelagibacter ubique

Creator:: Smith, Daniel P.
Abstract:: Batch cultures of Candidatus Pelagibacter ubique were grown under iron-, organosulfur-, and nitrogen-limiting conditions to understand how this ubiquitous marine bacterium responds to and interacts with environments where growth is limited by the availability of these nutrients. Global gene expression was monitored using microarrays and quantitative mass spectrometry to observe...
Resource Type:: Dissertation
Full Text:: time and between sites [12– 17]. Nitrogen (N) additions to oligotrophic waters also stimulated

A G-type Lectin Receptor-like Kinase Associated with Septoria Canker Resistance and Susceptibility Described using Multi-omics and Biotechnology

Creator:: Lenz, Ryan R.
Abstract:: Managers of forest and plantation ecosystems are encountering growing problems involving plant pathogens and the expanding geographic ranges of these pathogens. Historically unexposed stands are exceptionally vulnerable when a non-native pathogen is introduced because these pathogens can cause devastating disease in a host population that lacks co-evolved resistance mechanisms. One...
Resource Type:: Dissertation

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

Creator:: Carini, Paul J.
Abstract:: Members of the SAR11 clade of heterotrophic α-proteobacteria are ubiquitous and abundant in the world's oceans where they are thought to play a pivotal role in the global carbon cycle. The first SAR11 bacterium cultivated in vitro, 'Candidatus Pelagibacter ubique' HTCC1062 (Ca. P. ubique), was isolated by dilution into sterile...
Resource Type:: Dissertation
Full Text:: the raw materials (for example, core nutrients such as N, P and C) (25, 39, 40). Morris has put

ScholarsArchive@OSU

Cooperation and conflict in Pseudomonas aeruginosa quorum sensing

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Evolution of a streamlined cooperator in Pseudomonas aeruginosa quorum sensing

Quorum sensing gene regulation in Pseudomonas aeruginosa

The proteomic and transcriptomic responses to iron, sulfur, and nitrogen limitation in the abundant marine bacterium Candidatus Pelagibacter ubique

A G-type Lectin Receptor-like Kinase Associated with Septoria Canker Resistance and Susceptibility Described using Multi-omics and Biotechnology

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

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