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  • Optimization studies in preparative chromatography of biomolecules

    Creator:
    Ramanan, Sundar
    Abstract:
    Optimization of preparative nonlinear chromatography was carried out for the first time for a biomolecule mixture. Conventional wisdom on optimization, which roots from analytical chromatography, dictates optimizing resolution in an analytical column and obtaining similar separation in a large column for isolation. Such a method of optimization significantly under uses...
    Resource Type:
    Dissertation
    Full Text:
    also would like to thank Dr's Frank Chaplen, Mike Penner, Mike Schuyler and Arne Skaugset for