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Filtering by: Subject Time-of-flight mass spectrometry Remove constraint Subject: Time-of-flight mass spectrometry Committee Member Deinzer, Max Remove constraint Committee Member: Deinzer, Max

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  • Gas-phase fragmentation chemistry of protonated peptide ions

    Creator:
    Bythell, Benjamin James
    Abstract:
    The fragmentation characteristics of protonated peptides have been investigated using tandem mass spectrometry (MS/MS) under various fragmentation regimes and detailed density functional theory (DFT) reaction pathway calculations. The DFT calculations predict novel salt-bridge stabilized transition structures as well as consecutive reactions occurring in proton-bound dimers for some of the ions...
    Resource Type:
    Dissertation
    Full Text:
    …………………..............………....... 7 1.2.3.3 Time-of-flight Mass Spectrometry ………………….................... 8 1.2.3.3.1 MALDI

  • Development of fragmentation techniques in mass spectrometry for biological applications

    Creator:
    Ji, Hong
    Abstract:
    In this dissertation, I present the work of developing more efficient and economical techniques for fragmenting large bio-molecules, and ultimately making mass spectrometry a more powerful tool in proteomics, DNA sequencing, and other areas of biomolecular analysis. Aiming at lowering the installation and operating cost, and delivering electron capture dissociation...
    Resource Type:
    Dissertation
    Full Text:
    of ions in many other types of mass spectrometers, including time-of-flight and quadrupole