Index Catalog // ScholarsArchive@OSU

Comparative Metagenomic Investigations Link the Functional Capacity of the Gut Microbiome to Vertebrate Physiology

Creator:: Armour, Courtney R.
Abstract:: Microscopic organisms inhabit virtually every niche on this planet, where they perform functions vital to all life on earth. Accordingly, humans host a complex community of microorganisms (i.e. the gut microbiome) that inhabit the gastrointestinal tract and modulate host physiology. Insight into the specific mechanisms through which gut microbes influence...
Resource Type:: Dissertation
Full Text:: Gut Microbiome to Vertebrate Physiology Abstract approved

The Roles of Dietary Nitrate in Bone and the Gut in an Ovarian Hormone-deficient Rodent Model

Creator:: Conley, Melissa N.
Abstract:: Osteoporosis is a common metabolic bone disease, affecting a third of women and a fifth of men over age 65. In the US, annual health care costs associated with osteoporosis are estimated to be over $20 billion. Osteoporosis is associated with increased fracture risk, which has been demonstrated to predict...
Resource Type:: Dissertation
Full Text:: presented on June 8, 2016. Title: The Roles of Dietary Nitrate in Bone and the Gut in an Ovarian

Contractile function and calpain activity in mouse skeletal muscle during hypoxia

Creator:: Hu, Hui
Abstract:: Calcium activated proteases, or calpains, are activated in cardiac muscles under conditions of ischemia/reperfusion and hypoxia. Their activity in skeletal muscle under similar conditions is poorly understood. We tested the hypothesis that hypoxia elevates calpain-mediated proteolysis in isolated glycolytic (extensor digitorum longus, EDL) and oxidative (soleus, SOL) mouse muscles studied...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________ Jeffrey J. Widrick Calcium activated proteases, or calpains, are activated in cardiac

The genus Caenorhabditis : a system for testing evolutionary questions

Creator:: Raboin, Michael J.
Abstract:: Caenorhabditis elegans is arguably the best understood animal on the planet. Used for over 50 years to study development, we have a vast amount of knowledge of the inner workings of this worm. Our knowledge is incomplete, however, without placing this organism in its evolutionary and ecological context. In this...
Resource Type:: Dissertation
Full Text:: collected many of the C. briggsae strains used in chapter 3 and provided us with them. Larry J. Wilhelm

Use and Disclosure of Complementary Health Approaches Among Children with Developmental Disabilities

Creator:: Lindly, Olivia J.
Abstract:: Children with developmental disabilities (DD), particularly autism spectrum disorder (ASD), may use complementary health approaches (CHA), including some modalities that can be unsafe, inefficacious, and/or costly. Still, the prevalence of CHA use among US children with DD is not known and their reasons for use are not well understood. By...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Olivia J

Western Diet-Induced Nonalcoholic Steatohepatitis (NASH): The Impact of Time on the Onset and Remission of Disease

Creator:: Spooner, Melinda H.
Abstract:: Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...
Resource Type:: Dissertation
Full Text:: today without, are my greatest source of love and support. First, my husband Larry, boy what a ride

Identifying Differences in the Release of Bioactive Milk Peptides Across the Intestinal Tract Between Term and Preterm Infants

Creator:: Beverly, Robert L.
Abstract:: Premature birth interrupts the typical development of the human fetus, leaving the infant born with underdeveloped gastrointestinal and immune systems. Preterm infants have reduced stomach acidity, reduced digestive protease activity, more permeable intestinal membranes, impaired innate and adaptive immune response, and poor microbiome development. Due to these factors, preterm infants...
Resource Type:: Dissertation
Full Text:: induced by inflammation and infection (“leaky gut syndrome”), initiating a positive feedback loop that

DHA and Low-fat Low-cholesterol Diets as Treatment Strategies for Nonalcoholic Fatty Liver Disease

Creator:: Lytle, Kelli Anne
Abstract:: Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess neutral lipids within the parenchymal cells of the liver. The primary etiology is diet-induced and most often exists as a comorbidity with obesity, metabolic syndrome, and/or Type 2 Diabetes. The development of excess liver lipid can be self-limiting...
Resource Type:: Dissertation
Full Text:: Cholesterol ................................................................................ 20 1.3.4 Gut

The 2-Hydroxyestrone to 16α-Hydroxyestrone Ratio in Human Urine as a Biomarker of Cancer Chemoprevention Following Exposure to Brussels Sprouts and the Phytochemical, 3,3’-Diindolylmethane (DIM)

Creator:: Chen, Danny
Abstract:: Estrogen is a sex hormone responsible for the development and regulation of the reproductive system and secondary sex characteristics. They also play a critical role in the development of breast and uterine cancer. The formation of agonistic metabolites of estrogen, especially 16α-hydroxyestrone, have been found to have cancer-inducing effects meanwhile...
Resource Type:: Honors College Thesis
Full Text:: medications that affect gut motility or nutrient absorption (e.g. cholestyramine, sucralfate, pro-or anti

Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

Creator:: Luo, Ting
Abstract:: Metabolic syndrome is a problem affecting people around the world. In a number of studies, soy intake has been documented to possess antidiabetic and anticardiovascular effect. My project is focused on the impact of the intake of compounds found within soy, the isoflavones, their impact on metabolic syndrome symptoms, and...
Resource Type:: Dissertation
Full Text:: composition and the enzymatic capability of gut microflora (Heinonen et al., 2002; Atkinson et al. 2008

ScholarsArchive@OSU

Comparative Metagenomic Investigations Link the Functional Capacity of the Gut Microbiome to Vertebrate Physiology

The Roles of Dietary Nitrate in Bone and the Gut in an Ovarian Hormone-deficient Rodent Model

Contractile function and calpain activity in mouse skeletal muscle during hypoxia

The genus Caenorhabditis : a system for testing evolutionary questions

Use and Disclosure of Complementary Health Approaches Among Children with Developmental Disabilities

Western Diet-Induced Nonalcoholic Steatohepatitis (NASH): The Impact of Time on the Onset and Remission of Disease

Identifying Differences in the Release of Bioactive Milk Peptides Across the Intestinal Tract Between Term and Preterm Infants

DHA and Low-fat Low-cholesterol Diets as Treatment Strategies for Nonalcoholic Fatty Liver Disease

The 2-Hydroxyestrone to 16α-Hydroxyestrone Ratio in Human Urine as a Biomarker of Cancer Chemoprevention Following Exposure to Brussels Sprouts and the Phytochemical, 3,3’-Diindolylmethane (DIM)

Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

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