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Filtering by: Committee Member Karplus, P. Andrew Committee Member Kerkvliet, Nancy I.

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Creator:

Campbell, Yan

Abstract:

The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...

Resource Type:

Dissertation

Full Text:

Karplus and Dr. Kathy Magnusson. I thank Dr. Andy Karplus for your patience in answering my numerous
Analyses of noncanonical DNA structures

Creator:

Khuu, Patricia A.

Abstract:

The structural polymorphic nature of DNA has been long been recognized since the model of the right-handed B-DNA duplex proposed by James Watson and Francis Crick was accepted. Its malleability is thought to be critical in protein recognition and manipulation. In particular, it can form Holliday junctions, four-way DNA structural...

Resource Type:

Dissertation

Full Text:

P. Shing Ho, I thank my mentor, Dr. P. Shing Ho, for his support and guidance and, particularly