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Filtering by: Subject Bromomethane -- Toxicity testing Committee Member Kile, Molly

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Creator:

Tuttle, George R.

Abstract:

Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...

Resource Type:

Masters Thesis

Full Text:

Size and Surface Area Dependent Toxicity of Silver
Flavin-containing monooxygenase : metabolism and toxicity of anti-tuberculosis drug ethionamide in lung

Creator:

Singh, Priti B.

Abstract:

Multiple drug resistance (MDR) Tuberculosis (TB), leads to increased use of “second-line” drugs; one of the most effective is ethionamide (ETA). ETA is a prodrug metabolized by a mycobacterial flavin-containing monooxygenase (EtaA) as well human flavin-containing monooxygenases (FMOs). Of the five functional FMOs of humans, FMOs 1, 2, and 3...

Resource Type:

Masters Thesis

Full Text:

Flavin- Containing Monooxygenase: Metabolism and Toxicity