Index Catalog // ScholarsArchive@OSU

Creator:: Zhang, Yong
Abstract:: Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
Resource Type:: Dissertation
Full Text:: Phospholipase C-β Isozymes: Studies of Dimerization and Phosphatidylinositol 3,4,5-Trisphosphate Activation

Creator:: Geier, Mitra Celestine
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that occur in complex mixtures. These environmental mixtures can consist of both parent PAHs and their derivatives. Several parent PAHs are known or suspected mutagens and/or carcinogens, and a handful of PAH derivatives are known to be more potent mutagens and/or carcinogens...
Resource Type:: Dissertation
Full Text:: , writing, and study design. Chapter 2: Prepared by Mitra C. Geier with editorial comments provided

Creator:: Larsen, Christine A.
Abstract:: Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
Resource Type:: Dissertation
Full Text:: as follows: sema domain (S), cysteine-rich domain (C), immunoglobulin domains (Ig1-4

Creator:: Motorykin, Oleksii
Abstract:: In recent decades, there has been increased attention on human exposure to, and subsequently toxicity of, Polycyclic Aromatic Hydrocarbons (PAHs). PAHs are widespread organic pollutants and some have been shown to be toxic, carcinogenic and mutagenic. This research was focused on understanding the link between global PAH emissions and lung...
Resource Type:: Dissertation
Full Text:: , C) Alder × Smoke Shed, D) Alder × Tipi. .......................................... 49 Figure 3.4

Creator:: Saini, Gaurav
Abstract:: This research details laboratory assessment of bacterial hydrophobicity, variations in bacterial adhesion properties with growth and extended starvation as well as extension of this assay to colloidal hydrophobicity measurement. Hydrophobicity is an integral component of surface interactions and has been studied extensively for its role in a number of engineering...
Resource Type:: Dissertation
Full Text:: conditions, for strains: (a) MR-1, (b) JM 109, (c) D21, (d) D21f2.. 71 4.2 Variations in biomass (OD600

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