Index Catalog // ScholarsArchive@OSU

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: agent that is currently in phase Ill clinical trial is ecteinascidin 743 (11 ),22 isolated from the

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation
Full Text:: anticancer natural products are ecteinascidin 743 (10) and bryostatin 1 (11) (Tablel. I). The marine

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: Doublet DHiv Dihydroxyisovaleric acid DMSO Dimethylsulfoxide EC Effective Concentration EtOAc Ethyl

Creator:: Pham, Loan
Abstract:: The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of the...
Resource Type:: Dissertation

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