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Filtering by: Creator Allen, Stewart Remove constraint Creator: Allen, Stewart Committee Member Rockey, Daniel Remove constraint Committee Member: Rockey, Daniel

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  • Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

    Creator:
    Babrak, Lmar
    Abstract:
    Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
    Resource Type:
    Dissertation
    Full Text:
    molecules, homoserine lactone signaling molecules (Costerton, Stewart et al. 1999). Many clinical cases

  • Infectious diseases of the Felidae : parasite communities from miniature to massive

    Creator:
    Broughton, Heather M.
    Abstract:
    Direct anthropogenic stressors have caused drastic declines in wildlife populations over the past two centuries. In the face of these threats, spillover of infectious disease from domestic animals and livestock into wildlife, and novel interactions between parasites and pathogens within wildlife communities, have further suppressed already vulnerable populations. As management...
    Resource Type:
    Dissertation
    Full Text:
    Veterinary Medicine (OSU CVM) and the LL-Stewart Foundation; and to the OSU CVM class of 2013 for their

  • Molecular and cellular characterization of the intracellular phenotype of Mycobacterium avium

    Creator:
    Early, Julie V.
    Abstract:
    Mycobacterium avium cause disseminated disease in immunocompromised people such as AIDS patients. Subsequent to crossing the intestinal epithelium, M. avium thrive within vacuoles in macrophages. The bacteria exhibit a different, more invasive, phenotype after being in macrophages compared to M. avium from laboratory conditions. We hypothesized that this intracellular phenotype...
    Resource Type:
    Dissertation
    Full Text:
    -Koszycki S, Schlesinger PH, Chakraborty P, Haddix PL, Collins HL, Fok AK, Allen RD, Gluck SL, Heuser J

  • New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

    Creator:
    Banawas, Saeed S.
    Abstract:
    C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
    Resource Type:
    Dissertation

  • Evolutionary Genomic Responses to Mitochondrial Dysfunction in Caenorhabditis elegans

    Creator:
    Wernick, Riana I.
    Abstract:
    Understanding the impact of mitochondrial dysfunction on genome evolution has the potential not only to provide new insights on the basic evolutionary processes influencing mitochondrial and nuclear genomes, but may also reveal novel avenues for evolutionary adaptive recovery from harmful mutations. Aberrant mitochondrial activity is fundamental to the pathology of...
    Resource Type:
    Dissertation
    Full Text:
    tissues in an individual (Figure 1.2) (Stewart and Chinnery, 2015). The degree of heteroplasmy can