Index Catalog // ScholarsArchive@OSU

Creator:: Golonzhka, Olga
Abstract:: CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly understood roles in mouse development. CTIP2 is known to be highly expressed in the central nervous system, skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and exhibit defects in multiple organ systems...
Resource Type:: Dissertation
Full Text:: , skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and

Creator:: Zhang, Jinying
Abstract:: Quinolinate (QUIN) is an endogenous neurotoxic product of the kynurenine pathway of tryptophan metabolism. Quinolinate is a selective agonist of the NMDA family of glutamate receptors and, as such, may play a role in the pathology of a number of major central nervous system (CNS) disorders. These include both chronic...
Resource Type:: Masters Thesis
Full Text:: (Goldberg et al., 1987; Shalaby et al., 1989; Priestley, 1990; Berman and Murray, 1996). We chose

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation
Full Text:: -, monohydrochloride t Triplet TEA Trifluoroacetic acid TOCSY Total Correlation Spectroscopy tR Retention Time Tyr

Creator:: Ivancic, Monika
Abstract:: The solution structure determination of DNA molecules has been an important part of structural biology. NMR solution structures are a complement to structures solved via X-ray crystallography; the two methods are the only ways of obtaining three dimensional coordinates of macromolecules. Because of the nature of the molecule, the solution...
Resource Type:: Dissertation

Creator:: Roberts, Blaine R.
Abstract:: Oxygen derived radicals are involved in many aspects of life from aging and cell signaling to disease states as diverse as heart disease, diabetes, neurodegeneration and inflammation. Therefore, understanding the function of antioxidant defense proteins and the effects of oxygen derived radicals on protein function is essential to elucidate the...
Resource Type:: Dissertation

ScholarsArchive@OSU