Index Catalog // ScholarsArchive@OSU

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Creator:: Núñez, Oliva
Resource Type:: Masters Thesis
Full Text:: carcinogenesis 26 (Lee et al. 1989a, Nunez et al., in press). In the present study, autoradiographs showed

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:: Scheri, Richard C.
Abstract:: Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...
Resource Type:: Dissertation
Full Text:: . CONTRIBUTION OF AUTHORS Dr. Junga Lee assisted with sample collection and sample preparation for the

Suppression of Met signaling by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG)

Creator:: Larsen, Christine A.
Abstract:: Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
Resource Type:: Dissertation
Full Text:: , PDGF-BB, TGF and HGF [79, 80]. Lee et al. [81] showed that doses of EGCG as low as 7 µM in chronic

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

Creator:: Taft, Oriane Williams
Abstract:: Understanding how wetland birds use habitat is pivotal to developing successful and beneficial conservation strategies. Although it has been an ardent topic in forest research for some time, how species interact with the spatial patterning of habitat across a landscape (i.e., landscape structure) has been more or less neglected in...
Resource Type:: Dissertation
Full Text:: ), Carol Schuler (USFWS), Steve Smith (ODFW), and Tara Zimmerman (USFWS). Manuela Huso (OSU Forest

A role for ceramide accumulation in age-related cardiac mitochondrial dysfunction

Creator:: Monette, Jeffrey S.
Abstract:: Ceramides are a group of lipids in the sphingolipid family that are potent cell signaling molecules. Elevations in ceramide levels above the norm generally lead to apoptosis. Evidence from in vitro studies suggests that accumulation of ceramides within mitochondria leads to dysfunction of the mitochondria. This includes inhibition of the...
Resource Type:: Dissertation
Full Text:: Petersen Shay, Dove Keith, Brett Bemer, and Eric Smith, for the hard work, advice, and help that made

Biotransformation of 2,4,6-trinitrotoluene by ruminal organisms

Creator:: De Lorme, Marthah J. M.
Abstract:: 2,4,6-Trinitrotoluene (TNT) has been the common munitions used in the world and is an environmental contaminant that is amendable to reductive transformation reactions. The rumen is an extremely reductive environment containing diverse microbial populations. There are 21 pure culture ruminal bacteria species in culture collection, these were tested for the...
Resource Type:: Dissertation
Full Text:: . _____________________________________________________ Marthah De Lorme, Author CONTRIBUTION OF AUTHORS Dr. David Smith performed the

The effects of environmental stressors on cardiac gene expression and contractility in rainbow trout (Oncorhynchus mykiss)

Creator:: Momoda, Tracey S.
Abstract:: Rainbow trout (Oncorhynchus mykiss) experience a variety of stressors in their natural environment as well as in aquaculture that can have negative effects on their physiology. The effects of physiological stress and endocrine disruption have been well described in fish. However, there is a scarcity of information on the effects...
Resource Type:: Dissertation
Full Text:: , non-genomic actions (Lee et al., 2012). In ventricular myocytes from adult guinea pigs

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Creator:: Tsai, Hsi-Wen
Abstract:: Zebrafish (Brachydanio rerio) are small, freshwater teleost fishes in the family Cyprinidae, the true minnows. They are native to the tropical latitudes of India, but have become widespread through their use as aquarium fish and as models for several branches of biological research. Their ease of rearing, short generation time,...
Resource Type:: Dissertation
Full Text:: they were fed Oregon Test Diet (OTD) (Lee et al, 1991) twice daily and brine shrimp once daily. This

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Creator:: Shenvi, Swapna V.
Abstract:: Glutathione (GSH) is the predominant low molecular weight thiol antioxidant in liver tissue. GSH plays an important role in maintaining the intracellular thiol redox ratio as well as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P ≤ 0.05) in hepatocellular GSH levels. Using young (2-4...
Resource Type:: Dissertation
Full Text:: , Jeffrey Monette, Drs. Anthony Smith, and Jung Suh. To Du Heath and Judy Butler, thank you for your never

Regulation of NMDA-type glutamate receptors and MDR1 by two members of the EF-hand protein family

Creator:: Bajaj, Gaurav
Abstract:: EF-hand proteins are a conserved family of proteins that are modulated by divalent cations and regulate diverse cellular activities. In the present study we characterized the molecular determinants of myosin regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Myosin RLC is an EF-hand protein...
Resource Type:: Dissertation
Full Text:: stroke (Choi et al., 1988; Lee et al., 1999). In addition, NMDA type glutamate 3 receptors has

ScholarsArchive@OSU

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Suppression of Met signaling by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG)

Influence of wetland landscape structure of shorebirds wintering in an agricultural valley

A role for ceramide accumulation in age-related cardiac mitochondrial dysfunction

Biotransformation of 2,4,6-trinitrotoluene by ruminal organisms

The effects of environmental stressors on cardiac gene expression and contractility in rainbow trout (Oncorhynchus mykiss)

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Regulation of NMDA-type glutamate receptors and MDR1 by two members of the EF-hand protein family

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