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Filtering by: Creator Cox, Jane Remove constraint Creator: Cox, Jane Committee Member Zabriskie, Mark Remove constraint Committee Member: Zabriskie, Mark

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Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Creator:

Kulkarni, Sandhya N.

Resource Type:

Masters Thesis

Full Text:

: ycote Jane V. Aldrich This research was directed towards investigating the structure-activity
Synthetic strategies for the preparation of affinity label dynorphin A(1-11)NH₂ analogues

Creator:

Leelasvatanakij, Leena

Resource Type:

Dissertation

Full Text:

for the Preparation of Affinity Label Dynorphin A(1-11)NH2 Analogues. Abstract approved: Jane V
Bioactive Microbial Natural Products from Unique Indonesian Black Water Ecosystems

Creator:

Sheng, Yan

Abstract:

The discovery of new antibiotics reached its peak during the golden era of antibiotics in the mid 20th century and continued to thrive until the 1980s. However, after more than 50 years of fruitful exploration and exploitation of microbial natural products the discovery rate of new antibiotics has dropped drastically...

Resource Type:

Dissertation

Full Text:

Proteau, Dr. Jane Ishmael and Dr. Adrian Gombart for their generous time, support, advice and
Development and testing of novel anti-tubercular drugs

Creator:

Almabruk, Khaled Husain G.

Abstract:

Tuberculoѕiѕ (TB) iѕ a number one killer among treatable infectious diseases. It is caused by the pathogenic bacterium Mycobacterium tuberculoѕiѕ that primarily affects the lungѕ. It infects one third of the world population and kills approximately 2 million people each year (based on WHO report). Drug-reѕiѕtant TB haѕ become a...

Resource Type:

Masters Thesis

Full Text:

. I would like to thank my graduate committee members, Dr. Mark Zabriskie, Dr. Jane Ishmael, Dr
Biosynthesis and Rational Design of Novel Pactamycin Analogs

Creator:

Abugrain, Mostafa E.

Abstract:

Pactamycin, a potent antitumor antibiotic produced by the soil bacterium Streptomycespactum, is a structurally unique aminocyclopentitol-containing natural product. Itconsists of a highly functionalized cyclopentitol core unit, two aromatic rings [3-aminoacetophenone (3AAP) and 6-methylsalicylic acid (6MSA)], and a 1,1-dimethylurea moiety. Despite its potent biological activity, the development of thisantibiotic was hampered...

Resource Type:

Dissertation

Full Text:

, and did the antibacterial assay, as well as cloned and expressed the ptmD gene. Dr. Jane Ishmael did

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Academic Affiliation

College of Pharmacy5

Advisor

Mahmud, Taifo3
Aldrich, Jane V.2

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1996 to 2016

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Committee Member

Zabriskie, Mark[remove]5
Barofsky, Douglas1
Douglas, Markle1
Franklin, Paul1
Gills, John1
more Committee Members »

Creator

Abugrain, Mostafa E.1
Almabruk, Khaled Husain G.1
Kulkarni, Sandhya N.1
Leelasvatanakij, Leena1
Sheng, Yan1

Date

Date range begin – Date range end

Current results range from 1995 to 2015

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Decade

2010-20193
1990-19992

Degree Field

Pharmacy5

Degree Level

Doctoral3
Master's2

Degree Name

Doctor of Philosophy (Ph.D.)3
Master of Science (M.S.)2

Language

English [eng]5

License

All rights reserved3

Non-Academic Affiliation

Oregon State University. Graduate School5

Peer Reviewed

No5

Resource Type

Dissertation3
Masters Thesis2

Rights Statement

In Copyright3
Copyright Not Evaluated2

Subject

Opioids -- Receptors2
Streptomyces2
Affinity labeling1
Antineoplastic antibiotics -- Development1
Antineoplastic antibiotics -- Synthesis1
more Subjects »

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