Index Catalog // ScholarsArchive@OSU

Creator:: Wu, Xiumei
Abstract:: A gene cluster responsible for the biosynthesis of the antitumor agent cetoniacytone A was identified in Actinomyces sp. strain Lu 9419, an endosymbiotic bacteria isolated from the intestines of the rose chafer beetle. The nucleotide sequence analysis of the 26 Kb DNA region revealed the presence of 17 complete ORFs,...
Resource Type:: Dissertation

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation

Creator:: Medina, Rebecca A.
Abstract:: This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites. A collection of the marine cyanobacterium Lyngbya majuscula from the Radames Islands, Madagascar yielded two new cyclic depsipeptides, radamamides A and B,...
Resource Type:: Dissertation

Creator:: Andrianasolo, Eric Hajaniriana
Abstract:: This thesis is an investigation of the natural products deriving from marine algae and cyanobacteria and has resulted in the discovery of eleven new secondary metabolites. The structure elucidations of these new molecules were performed using a variety of spectroscopic techniques. Four new macrolides were isolated and characterized from the...
Resource Type:: Dissertation

Creator:: Thornburg, Christopher C.
Abstract:: Metagenomics has revealed that the marine microbial biosphere is immensely more diverse than originally considered, and is an almost untapped reservoir for the potential discovery of microbial natural products. Despite numerous advances in culturing, biosynthetic engineering and genomic-based screening efforts to uncover much of this diversity in relatively accessible environments,...
Resource Type:: Dissertation

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