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Filtering by: Creator Duker, Dick C. Contributor Danelishvili, Lia

Quantitative Analysis of Mycobacterium avium subsp. hominissuis and Mycobacterium abscessus subs. abscessus Proteome in Response to Antibiotics and During Exposure to Different Environmental Conditions

Creator:

Rojony, Rajoana

Abstract:

M. avium subsp. hominissuis (MAH) and M. abscessus subsp. abscessus (MAB) both belong to the clinically important non-tuberculous mycobacterial (NTM) group that infect immunocompromised patients with AIDS and individuals with underlining lung conditions such as bronchiectasis or cystic fibrosis. The main challenge of treating MAH and MAB patients is an...

Resource Type:

Masters Thesis

Full Text:

. 6 References: [1] N. Rastogi, E. Legrand, and C. Sola, “The mycobacteria : an
Mycobacterium abscessus genetic determinants associated with intrinsic resistance to antibiotics

Creator:

Gorzynski, Mylene

Abstract:

M. abscessus subsp. abscessus is a nontuberculous mycobacterium causing pulmonary infections in immunocompromised patients. The treatment of MAB infections is challenging due to its natural resistance to most antibiotics. To identify MAB genetic factors that are involved in mechanisms of the antibiotic tolerance, we screened the library of 2,000 gene...

Resource Type:

Honors College Thesis

Full Text:

, bacteria was grown at 37°C in 7H9 broth supplemented with 10% OADC and 0.1% Tween-80 with shaking at 200