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Filtering by: Creator Silva, George Contributor Shulzhenko, Natalia

Identification of Cervical Cancer Key Regulators using Network Biology Approach

Creator:

Vyshenska, Dariia

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause of the disease. Currently available treatment methods are limited and emphasize the need for discovery of new therapies that improve patient outcome. Chromosomal amplifications have been identified as a source of...

Resource Type:

Dissertation
Western Diet-Induced Nonalcoholic Steatohepatitis (NASH): The Impact of Time on the Onset and Remission of Disease

Creator:

Spooner, Melinda H.

Abstract:

Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...

Resource Type:

Dissertation