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Filtering by: Committee Member Edwards, J. A. Remove constraint Committee Member: Edwards, J. A. Contributor sim Iwaniec, Urszula T. Remove constraint Contributor sim: Iwaniec, Urszula T.

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  • Homeodomain Transcription Factor Pitx2 is Required for Muscle Maintenance and Energy Homeostasis

    Creator:
    Lattier, Vera C.
    Abstract:
    Skeletal muscle, the largest organ in the body in mass, is composed by 600 specialized muscles in humans with unique biochemical, physiological and metabolic identities. Skeletal muscles control body movement, locomotion, and nutrient balance. Muscle formation requires precisely orchestrated environmental signals and regulatory gene networks in time and space. Gene...
    Resource Type:
    Dissertation
    Full Text:
    perturbations result in myopathies and systemic metabolic diseases. Pitx2, a homeobox gene, is expressed in