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Filtering by: Advisor Fitzgerald, Stephen A. Creator Choudhury, Mudra

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

. Abstract approved: ______________________________________________________ Stephen A. Ramsey
The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

. Abstract approved: ______________________________________________________ Stephen A. Ramsey