The ascomycete Geosmithia morbida and the walnut twig beetle Pityophthorus juglandis are associated with thousand
cankers disease of Juglans (walnut) and Pterocarya (wingnut). The disease was first reported in the western United States
(USA) on several Juglans species, but has been found more recently in the eastern USA in the...
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Fungal hyphae are among the most highly polarized cells. Hyphal polarized
growth is supported by tip-directed transport of secretory vesicles, which accumulate temporarily
in a stratified manner in an apical vesicle cluster, the Spitzenkörper. The exocyst complex
is required for tethering of secretory vesicles to the apical plasma membrane. We...
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con-
tain glucan synthase activity (Verdin et al., 2009; Sánchez-León
et al., 2011). To study the
Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway
in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we
ectopically expressed a constitutively active zebrafish Smoothened (Smoa1) in neural progenitor cells and analyzed...
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There is a lack of consensus regarding the roles of sulfide saturation versus volatile degassing on the partitioning of Cu and Ag during differentiation and eruption of convergent margin magmas. Because of their oxidized character, volatile-rich magmas from the Eastern Manus Back-arc Basin (EMBB) only reach sulfide saturation following magnetite-driven...
Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species’ threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that...
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Konstans Wells233,234, Christopher D. Williams235, Michael R. Willig236,237, John C. Z
BACKGROUND: On the basis of the 2014 guidelines for hypertension therapy in the United States,
many eligible adults remain untreated. We projected the cost-effectiveness of treating
hypertension in U.S. adults according to the 2014 guidelines.
METHODS: We used the Cardiovascular Disease Policy Model to simulate drug-treatment and
monitoring costs, costs...
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Medical
Association. 2001;286:180‐187.
15. Liu J, Hong Y, D'Agostino RBS, Wu Z, Sun J, Wilson PW
Convergent evolution is common throughout the tree of life, but the molecular mechanisms
causing similar phenotypes to appear repeatedly are obscure. Yeasts have arisen in multiple
fungal clades, but the genetic causes and consequences of their evolutionary origins are
unknown. Here we show that the potential to develop yeast forms...
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genomics. Nat. Rev. Genet. 11, 512–524 (2010).
8. Sanchez-Martinez, C. & Perez-Martin, J. Dimorphism in
Resolving the debate surrounding the nature and controls of seasonal variation in the structure and metabolism of Amazonian rainforests is critical to understanding their response to climate change. In situ studies have observed higher photosynthetic and evapotranspiration rates, increased litterfall and leaf flushing during the Sunlight-rich dry season. Satellite data...
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B,
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2012
Microbial communities are responsible for the bulk of biogeochemical processing in temporary headwater streams, yet there is still relatively little known about how community structure and function respond to periodic drying. Moreover, the ability to sample temporary habitats can be a logistical challenge due to the limited capability to measure...