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Filtering by: Subject Developmental genetics Remove constraint Subject: Developmental genetics Creator Franzosa, Jill A. Remove constraint Creator: Franzosa, Jill A.

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  • Consequences of miRNA misregulation on embryonic development and aging

    Creator:
    Franzosa, Jill A.
    Abstract:
    microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
    Resource Type:
    Dissertation
    Full Text:
    developmental stages. First, to uncover the potential role of miRNAs in teratogenicity, we investigated