Tn5 mutagenesis of apdA (for antibiotic production) and deletion of
gacA (for global antibiotic and cyanide) resulted in the same pleiotropic phenotype in
Pseudomonas fluorescens (i.e. production of an array of secondary metabolites
including the antibiotics pyrrolnitrin, pyoluteorin, and 2,4-diacetylphloroglucinol as
well as a tryptophan-side-chain oxidase, hydrogen cyanide, and an...