Background:
The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies.
Results:
Wild type...
Background:
The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies.
Results:
Wild type...
Background:
The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies.
Results:
Wild type...
Background:
The dietary agent sulforaphane (SFN) has been reported to induce nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)-dependent pathways as well as inhibiting histone deacetylase (HDAC) activity. The current investigation sought to examine the relationships between Nrf2 status and HDAC expression in preclinical and translational studies.
Results:
Wild type...
Consuming cruciferous vegetables such as broccoli sprouts, kale, Brussels sprouts, and bok choy is associated with several health benefits, such as a decreased risk of certain cancers. Cruciferous vegetables contain the glucosinolate, glucoraphanin (GFN). Cutting, chopping or chewing these vegetables releases the enzyme myrosinase, which transforms GFN into sulforaphane (SFN)....
Consuming cruciferous vegetables such as broccoli sprouts, kale, Brussels sprouts, and bok choy is associated with several health benefits, such as a decreased risk of certain cancers. Cruciferous vegetables contain the glucosinolate, glucoraphanin (GFN). Cutting, chopping or chewing these vegetables releases the enzyme myrosinase, which transforms GFN into sulforaphane (SFN)....
Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2.
EZH2 functions in the...
Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2.
EZH2 functions in the...
Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2.
EZH2 functions in the...
Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2.
EZH2 functions in the...