The etiology of canine gallbladder mucocele (GBM) has not yet been identified. However, several studies
have linked GBM in dogs to particular breeds (Shetland Sheepdogs are commonly implicated), concurrent endocrine disease
(hyperadrenocorticism and/or hypothyroidism), and a mutation in the canine ABCB4 gene (ABCB4 1583_1584G), particularly
in Shetland Sheepdogs. The current...