Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...