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Filtering by: Creator Osborn, Andrew Remove constraint Creator: Osborn, Andrew Degree Level Bachelor's Remove constraint Degree Level: Bachelor's

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  • Investigations of Pactamycin Biosynthesis

    Creator:
    Osborn, Andrew
    Abstract:
    Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
    Resource Type:
    Undergraduate Thesis and Presentation