Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
The importance of high blood pressure (BP) and the effect of BP lowering in older adults remain controversial due to the mixed evidence in this population. Frailty status may resolve the apparently conflicting findings and identify subpopulations who share common risk. Emerging evidence demonstrates that low BP is associated with...
BACKGROUND: Whether limitation in ability to perform activities of daily living (ADL) or gait speed can identify subgroups of elders in whom the association of systolic (SBP) and diastolic (DBP) blood pressure with cardiovascular events and death differs is not well established.
METHODS: We evaluated whether ADL and gait speed...
BACKGROUND: Chronic kidney disease (CKD) and hyperuricemia often coexist and both conditions are increasing in prevalence in the U.S., although their shared role on cardiovascular risk remains highly debated.
STUDY DESIGN: Cross-sectional and longitudinal
SETTING AND PARTICIPANTS: Participants in the National Health and Nutrition Examination Survey (NHANES) from 1988 to...
Objectives:
To examine the association between kidney function and all-cause mortality in octogenarians.
Design
Retrospective analysis of prospectively collected data.
Setting:
Community.
Participants:
Serum creatinine and cystatin C were measured in 1,053 Cardiovascular Health Study (CHS) All Stars participants.
Measurements:
Estimated glomerular filtration rate (eGFR) was determined using the Chronic...