2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent immunosuppressant, and suppresses many disease models including graft-versus-host (GVH), experimental autoimmune encephalomyelitis (EAE) and a model of type 1 diabetes in non-obese diabetic (NOD) mice (1-3). In this study, we show that the inflammation of the pancreas due to insulitis is not a systemic autoimmune...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent immunosuppressant, and suppresses many disease models including graft-versus-host (GVH), experimental autoimmune encephalomyelitis (EAE) and a model of type 1 diabetes in non-obese diabetic (NOD) mice (1-3). In this study, we show that the inflammation of the pancreas due to insulitis is not a systemic autoimmune...
Mycobacterium avium subsp. hominissuis (MAH) is an environmental bacteria that infects immunocompromised humans. MAH cases are increasing in incidence, making it crucial to gain knowledge of the pathogenic mechanisms associated with the bacterium. MAH infects macrophages and after several days the infection triggers the phagocyte apoptosis. Many of the intracellular...
M. avium is an opportunistic pathogen that primarily infects macrophages. In order to survive within the macrophage, M. avium secretes proteins into the host cell cytoplasm to inhibit specific functions such as phagosome acidification, altering pathways as well as initiating apoptosis. However, little is known about how those secreted proteins...
In organizational management, researchers and managers study separations or faultlines that occur in diverse teams when members
form subgroups based on the alignment of multiple demographic characteristics. The team faultline concept is operationalized
using multivariate cluster analysis—analysts use faultline measures to identify subgroups/clusters in a team and to quantify how...
Long-term ecological data are crucial in helping ecologists understand ecosystem function and environmental change. Nevertheless, these kinds of data sets are difficult to analyze because they are usually large, multivariate, and spatiotemporal. Although existing analysis tools such as statistical methods and spreadsheet software permit rigorous tests of pre-conceived hypotheses and...
Personality traits and daily self-regulation of health goals, social goals, and perceived stress were examined over 100 days to better understand how traits may influence self-regulation. This study was conducted with a sample of 99 older adults via web-based surveys. Results showed that, as predicted, traits of neuroticism, conscientiousness, and...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent immunosuppressant, and suppresses many disease models including graft-versus-host (GVH), experimental autoimmune encephalomyelitis (EAE) and a model of type 1 diabetes in non-obese diabetic (NOD) mice (1-3). In this study, we show that the inflammation of the pancreas due to insulitis is not a systemic autoimmune...