A two-part study was conducted to investigate some of the nutritional
relationships between dietary tri-o-cresylphosphate (TOCP), a
toxic stress material, and dietary vitamin E and selenium. In part
one, growth rate of male weanling Long-Evans rats and day-old
Japanese quail (Coturnix coturnix japonica) was used to determine the
protective action...
The metabolism of pyrrolizidine alkaloids and other
drugs was studied with regard to nutritional status and
species differences. Pyrrolizidine alkaloids which are biotransformed
to severely toxic metabolites were isolated
from tansy ragwort (Senecio jacobaea). Semi-purified alkaloid
crystals containing five alkaloids (senecionine, seneciophylline,
jacobine, jacoline, and jacozine) were prepared
and found...