Index Catalog // ScholarsArchive@OSU

Fabrication and application of polymer based microfluidic devices

Creator:: Koesdjojo, Myra T.
Abstract:: The concept of reducing laboratory operations in scale such that they fit on a microfluidic chip has been met with great enthusiasm. Lab-on-a-chip devices promise to be cost effective to operate due to reduced reagent consumption, have the potential to offer shorter analysis times due to their short path lengths,...
Resource Type:: Dissertation
Full Text:: ACKNOWEDGEMENTS First and foremost, my deepest gratitude goes to my research advisor, Dr. Vincent Remcho

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Creator:: Hutanu, Daniela
Abstract:: The emerging field of nanotechnology strictly requires the micro-scaling of the available separation technology and the design of novel devices for separations of molecules of interest. The separation of proteins and nanoparticles is challenging due to their relatively large size, non-specific adherence to surfaces and instability in many solvents. This...
Resource Type:: Dissertation
Full Text:: approved: Vincent T. Remcho The emerging field of nanotechnology strictly requires the micro

Novel monolithic columns for microscale liquid chromatography and capillary electrochromatography

Creator:: Chirica, Gabriela S.
Abstract:: The challenges prompted by miniaturization of chromatographic systems have led scientists to explore new avenues in the synthesis of stationary phases. Packed capillary columns have found limited application in routine analysis due to a number of technical difficulties, most of which are attributable to the frits. New column designs insure...
Resource Type:: Dissertation
Full Text:: advisor, Dr. Vincent T. Remcho. With his patience, knowledge and friendship he conveyed to me his passion

RNA and DNA aptamers as affinity stationary phases for liquid chromatography and capillary electrochromatography

Creator:: Clark, Stacey L.
Abstract:: Due to a number of disadvantages associated with the use of antibodies as affinity stationary phases, researchers have recently began to explore the use of RNA and DNA aptamers for use as affinity stationary phases. These molecules have been shown to be a viable choice for applications in many methods...
Resource Type:: Dissertation
Full Text:: : Vincent T. Remcho Due to a number of disadvantages associated with the use of antibodies as affinity

Monolithic sorbents for microscale separations

Creator:: Doneanu, Angela
Abstract:: Over the last decade, the miniaturization of analytical systems has become an increasingly important and interesting research area. Miniaturized systems offer many advantages, including reduced reagent and sample consumption, shorter analysis times, portability and disposability. This dissertation describes novel approaches in this direction, focusing on two areas: the miniaturization of...
Resource Type:: Dissertation
Full Text:: First I want to express my gratitude to my adviser, Dr. Vincent Remcho, who provide my with his

Novel approaches to enhancing selectivity and efficiency in microscale liquid chromatography

Creator:: Vallano, Patrick T.
Abstract:: For a number of reasons, miniaturization of chromatographic columns has been a general trend over the past three decades. Methods designed to enhance selectivity and efficiency can offer improved separation power and speed, expanding on the advantages of miniaturized columns. This dissertation describes novel approaches in this direction, focusing on...
Resource Type:: Dissertation
Full Text:: Selectivity and Efficiency in Microscale Liquid Chromatography. Abstract approved: Vincent T. Remcho For a

Employing capillary electrophoresis as a separation method for pharmaceutical analysis

Creator:: Lessard, Laura L.
Abstract:: Capillary electrophoresis as a technique has many applications in a broad range of fields including forensics, environmental analysis, and biological analysis and as a separation method for samples such as oligonucleotides, peptides, proteins, and pharmaceuticals. The research conducted herein is for the antibiotic pharmaceutical ciprofloxacin HCl and three impurities. Sample...
Resource Type:: Masters Thesis
Full Text:: Separation Method for Pharmaceutical Analyses Abstract approved: Vincent T. Remcho Capillary

From electrophoresis to dielectrophoresis: designing, fabricating, and evaluating an electroformed ratchet type microfluidic dielectrophoresis device

Creator:: Gonzalez, Carlos F.
Abstract:: Dielectrophoresis (DEP) is a separation method in which a non-uniform electric field is used to induce a dipole moment in a suspended particle. If the polarization of the particle is greater than that of the suspending medium, the particle will move towards the region of higher field strength (positive DEP);...
Resource Type:: Dissertation
Full Text:: : Vincent T. Remcho Dielectrophoresis (DEP) is a separation method in which a non-uniform electric

Design, fabrication and application of a microfluidic nanofiltration module for separation and purification of macromolecules and nanoparticles

Creator:: Rundel, Jack T.
Abstract:: A microfluidic nanofiltration module has been designed, fabricated and applied to the continuous-flow, pressure-driven, post-synthetic purification of macromolecules and nanoparticles via diafiltration using a commercially available organic solvent resistant nanofiltration membrane, STARMEM 122. This module will readily interface with other microscale components within a "nanofactory" for the rapid synthesis, purification...
Resource Type:: Dissertation
Full Text:: : ______________________________________________________ Vincent T. Remcho A microfluidic nanofiltration module has been designed, fabricated and

Development of materials and devices for separation of polyamido[a]mine dendrimers

Creator:: Tennico, Yolanda H.
Abstract:: Over the last decade, the use of highly branched macromolecules, called dendrimers, is emerging. Polyamidoamine (PAMAM) dendrimers, in particular, have attracted high interest due to their unique properties, such as well-defined size, shape, and solubility in water. Our group, as part of an interdisciplinary team, is currently working on developing...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

Fabrication and application of polymer based microfluidic devices

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Novel monolithic columns for microscale liquid chromatography and capillary electrochromatography

RNA and DNA aptamers as affinity stationary phases for liquid chromatography and capillary electrochromatography

Monolithic sorbents for microscale separations

Novel approaches to enhancing selectivity and efficiency in microscale liquid chromatography

Employing capillary electrophoresis as a separation method for pharmaceutical analysis

From electrophoresis to dielectrophoresis: designing, fabricating, and evaluating an electroformed ratchet type microfluidic dielectrophoresis device

Design, fabrication and application of a microfluidic nanofiltration module for separation and purification of macromolecules and nanoparticles

Development of materials and devices for separation of polyamido[a]mine dendrimers

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