Xenobiotic exposures may induce alternative splicing in the pre-mRNA of nuclear hormone receptor (NHR) genes, yielding unpredictable patterns of gene expression that may promote adverse drug events and promote environmental disease. Informed by observations in the androgen receptor (AR; class I NHR), whereby alternatively-spliced AR transcripts induce ligand-independent hormone signaling...
The Marinoan Snowball Earth ended 635 Ma ago during the Neoproterozoic Era, after an interval in which the Earth was completely covered by glaciers. Thawing of these glaciers formed cap carbonates across shallow marine depositional environments. The Noonday Formation is a cap carbonate that formed after the deglaciation of the...
Background/Purpose: A variety of models have been proposed to understand individuals with disabilities. Although it is important to consider the perspective of disability each model presents, the social model has gained considerable attention. This model explains disability as limitations and restrictions of society and the environment. A subset of the...
A novel approach for the colorimetric detection of creatinine in a paper/polycaprolactone hybrid microfluidic device using alkaline3,5-dinitrobenzoate (DNB) is described. The reaction parameters of reagent concentration, alkalinity, and analysis time are optimized for fast reaction times and high color yield. Microfluidic devices incorporating this assay are designed and fabricated to...
Utilization and preference of whelk shells by the hairy hermit crab are examined in the following to further define the ecology of Oregon’s mid to low intertidal ecosystems. The study was conducted at Tokatee Kloochman State Natural Area (TK) where I made observations before collecting data. My observations were of...
The purpose of this thesis was to determine if an underlying biological cause exists for the exuberant reproductive success in free-roaming unowned (FRU) cats. The hypothesis for this thesis was that FRU tom and queen cats have reproductively adapted to man-made sterilization efforts by lowering the age at which they...