Modern day digital systems employ frequency
synthesizers to provide a common clock to the system.
They are undergoing large scale integration due to which, mitigation
of the effect of noise on power supply has become a major design consideration
in clocking circuits. Rapid scaling of CMOS technology mandates the
design...
Azaspiracid has generated an enormous amount of scientific interest in the fourteen years since its initial discovery. The structure contains a 6,5,6 bis-spiroketal, a [3.3.1] bicyclic ketal and a 6,5-spiroaminal linkage as key moieties. With 9 rings, 20 stereocenters and three alkenes, the azaspiracid immediately attracted the interest of the...
This dissertation presents an incremental analog-to-digital converter (ADC) with digital digital-to-analog converter (DAC) mismatch correction. A theoretical time-domain analysis technique was developed to predict the noise performance of the incremental ADC, and a new optimization technique was proposed to minimize the output noise.
In the calibration mode, the incremental ADC...
A proposed state-and-transition model (STM) for the Deep Sand Savannah ecological site in central New Mexico was developed using historical data and expert knowledge. This STM was tested utilizing data from short and long term one-seed juniper (Juniperus monosperma (Engelm.) Sarg.) control experiments initiated in 1981 and 1985. Utilizing data...
A relatively new model of error control is the limited magnitude error over high radix channels. In this error model, the error magnitude does not exceed a certain limit known beforehand. In this dissertation, we study systematic error control codes for common channels under the assumption that the maximum error...
The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Little, if any, quantifications have been made on the contribution of the vertebral column during jumping in quadrupedal mammals. Previous studies of jumpers have focused on the morphological and physiological specializations of the hindlimbs. In this study, such specialization was measured during the supramaximal jumps of the Pacific jumping mouse...
Depleted species of rockfish (Sebastes spp.) from the Northeast Pacific experience high discard mortality due to "barotrauma," induced from the rapid change in pressure during capture. Research suggests rockfish have the potential to survive barotrauma if immediately recompressed, but the potential for long-term recovery is unknown. In this project, we...
Transient liquid-phase diffusion brazing is used in precision, hermetic joining applications as a replacement for diffusion bonding to reduce cycle times, reduce bonding pressure and improve yields. Studies showed that the interlayer used in diffusion brazing can be detrimental due to the use of melting point depressants (MPDs). The goal...
Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...