Retraction fibers (RFs) determine orientation of the cell division axis and guide the spreading of daughter cells. Long and unidirectional RFs, which are especially apparent during mitosis of cells in three-dimensional (3D) environments, enable improved control over cell fate, following division. However, 3D gel environments lack the cues necessary for...
The complexity of designing and testing today's system on chip (SOC) is increasing due to greater integrated circuit (IC) density and higher IO and memory frequencies. SOCs for the mobile phone and tablet market have the unique challenge of short product development windows, at times less than six months, and...
Ultra-wideband (UWB) radio has become an attractive alternative for wireless communications due to the robustness to multipath fading, low power transmission, mostly-digital implementation, and low cost. Furthermore, short-range, high data-rates applications are possible with UWB radios due to the wide spectral
allocations at 3.1 - 10.6 GHz.
This thesis presents...
High speed serial links are critical components for addressing the growing demand for I/O bandwidth in next-generation computing applications, such as many-core systems, backplane and optical data communications. Due to continued process scaling and circuit innovations, today's CMOS serial link transceivers can achieve tens of Gb/s per pin. However, most...
For the past half century, CMOS process scaling has followed Moore's law, approximately doubling transistor density every 18 months. While locally routed wires have generally scaled with transistor size, longer wires have scaled at a slower rate and in some cases have grown larger as chip size and complexity have...
The problem of footstep level resolution indoor path tracking and gait velocity
lacks a good solution. The current solutions are either prohibitively expensive [4],
extremely invasive to deploy [1], or too inaccurate to achieve the sub meter level
resolution required to track foot paths. By combining existing pedestrian dead
reckoning...
As computation power continues to grow, the demand for data transfer bandwidth is also rising. This is reflected in the increasing data-rate of high-speed links. However, the increase in data-rate is sustainable only if the I/O energy efficiency improves as well. This dissertation explores several techniques to enable high-speed links...
Scaling the supply voltage into the sub/near-threshold domain is one of the most effective methods for improving the energy efficiency of next-generation electronic microsystems. Unfortunately, the relationship between low-voltage operation and radiation-induced soft error rate is not widely known, as little research has been previously performed and reported for soft-error...
An innovative silver nano-dimple arrays (Ag DAs)-integrated microfluidic device was developed to achieve highly sensitive fluorescence-based nucleic acid detection. The Ag DAs were utilized to produce surface plasmon resonance (SPR) for strong fluorescence enhancement. We systematically investigated the plasmon-enhanced fluorescence by controlling the nanostructure dimension of the Ag DA substrate....
Ultrawideband (UWB) communication is a promising technology for wireless body area networks (BANs), especially for applications that require transmission of both low and high data rates with excellent energy efficiency. Therefore, understanding the unique UWB channel propagation characteristics around the human body is critical for a successful wireless system, especially...