Index Catalog // ScholarsArchive@OSU

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Creator:: Kim, Jeonghwan
Abstract:: Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
Resource Type:: Dissertation
Full Text:: delivery of mRNA is lipid nanoparticles (LNPs). LNPs enable safe and efficient gene delivery; however

Seeing Genes: Multiscale Phenotyping Reveals Gene Functions in Maize Pollen

Creator:: Warman, Cedar D.
Abstract:: Plant sexual reproduction requires a broad array of molecular mechanisms to proceed successfully. Some of these mechanisms are well-studied, but our knowledge of them as a whole is fundamentally incomplete. Pollen tube growth is a key part of this process, facilitating the delivery of the sperm cells to the female...
Resource Type:: Dissertation
Full Text:: . Title: Seeing Genes: Multiscale Phenotyping Reveals Gene Functions in Maize Pollen. Abstract

Identification and Occurrence of Sweet Cherry (Prunus avium) Virus and Virus-Like Diseases in Various Regions and Orchards of Oregon

Creator:: Reinhold, Lauri A.
Abstract:: There are over 35 known virus and virus-like diseases of sweet cherry (Prunus avium), some with potential to cause severe economic impact by reducing vegetative growth, vigor, and/or quality of fruit. Oregon is the second-ranked state for sweet cherry production in the United States with 13,000 acres and $70.8 million...
Resource Type:: Dissertation
Full Text:: presented on July 31, 2020. Title: Identification and Occurrence of Sweet Cherry (Prunus avium) Virus

Non-viral Vectors for Ocular Gene Delivery

Creator:: Herrera-Barerra, Marco, F.
Abstract:: Nucleic acid therapeutics has cemented itself as one of the most efficacious and robust avenues for treatment of a wide range of diseases from vaccine development to treatment of liver, retina, cancer applications. Non-viral mediated gene delivery using lipid-based nanoparticle (LNP) carriers has proven its compatibility with addressing unexpected, fast...
Resource Type:: Dissertation
Full Text:: classified by the type of cell affected, the gene or groups of genes with a genetic aberration, its

Gene Structure and Expression of the Rice S-Domain Kinase (SD-RLK) Gene Subfamily

Creator:: Dikeman, Daemon
Abstract:: The S-domain subfamily of receptor-like kinases (SD-RLKs) in plants is poorly characterized and the majority of genes have unknown functions. The goal of this study was to study the expansion of rice (Oryza sativa) SD-RLK subfamily, and characterize gene and protein structure and expression of its members using publicly available...
Resource Type:: Honors College Thesis
Full Text:: ) are encoded by members of a large gene family, the RLK gene family, in plants that include genes

Inheritance and Allelism Among the B genes in Cucurbita moschata

Creator:: Wilson, Casey K.
Abstract:: One of the most economically important genes in squash (Cucurbita spp.) is the B gene which conditions precocious depletion of chlorophyll in preanthesis fruit. The B genes are found naturally occurring in at least three of the five domesticated species of Cucurbita, including C. pepo, C. maxima and, most recently...
Resource Type:: Masters Thesis
Full Text:: the B gene which conditions precocious depletion of chlorophyll in preanthesis fruit. The B genes

Evaluation of grapevine red blotch virus epidemiology with reference to potential insect vectors

Creator:: Dalton, Daniel T.
Abstract:: Grapevine red blotch virus (GRBV), the causal agent of red blotch disease (RBD) in grapevine, Vitis vinifera L., is an emerging pathogen of significance to the wine grape industry of Oregon, USA. To address knowledge gaps of GRBV epidemiology, spread of GRBV was evaluated in Oregon vineyards over four years....
Resource Type:: Dissertation
Full Text:: 14, 2020. Title: Evaluation of Grapevine red blotch virus Epidemiology with Reference to

A Putative PAMP-Induced Peptide Family Member is Associated with Symptom Severity to the Necrotic Strain NTN of Potato Virus Y in Potato

Creator:: Combest, Max M.
Abstract:: Potato Virus Y (PVY) is an enduring problem for potato production worldwide. Potato varieties that resist the “ordinary” strain PVYO were developed by breeders, but in recent years, recombinant strains of PVY have been able to circumvent this strain-specific resistance and evade growers and seed certification officials by causing fewer...
Resource Type:: Masters Thesis
Full Text:: confer ER17. Those conferring HR are known as N-genes. N-gene-mediated HR is associated with

StPIP1, a PAMP-induced peptide in potato, elicits plant defenses and is associated with disease symptom severity in a compatible interaction with potato virus Y

Creator:: Combest, Max M., Moroz, Natalia, Tanaka, Kiwamu, Rogan, Conner J., Anderson, Jeffrey C., Thura, Lin, Rakotondrafara, Aurélie M., and Goyer, Aymeric
Abstract:: The role of small secreted peptides in plant defense responses to viruses has been seldom investigated. Here, we report a role for potato (Solanum tuberosum) PIP1, a gene predicted to encode a member of the PAMP-induced peptide (PIP) family, in the response of potato to potato virus Y infection (PVY)....
Resource Type:: Article
Full Text:: factors, Hsr203J 518 (an HR marker gene), glucanases, and Hcr2-0A-annotated resistance genes

Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host Factors

Creator:: Nutter, Laura
Abstract:: Streptococcus pneumoniae and Influenza A Virus both primarily infect the upper respiratory tract, with more severe disease occurring during coinfection than would be caused by either pathogen independently. Until recently, characterization of the interactions between these two pathogens has occurred exclusively in the context of a host or using host-derived...
Resource Type:: Masters Thesis
Full Text:: : Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host

ScholarsArchive@OSU

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Seeing Genes: Multiscale Phenotyping Reveals Gene Functions in Maize Pollen

Identification and Occurrence of Sweet Cherry (Prunus avium) Virus and Virus-Like Diseases in Various Regions and Orchards of Oregon

Non-viral Vectors for Ocular Gene Delivery

Gene Structure and Expression of the Rice S-Domain Kinase (SD-RLK) Gene Subfamily

Inheritance and Allelism Among the B genes in Cucurbita moschata

Evaluation of grapevine red blotch virus epidemiology with reference to potential insect vectors

A Putative PAMP-Induced Peptide Family Member is Associated with Symptom Severity to the Necrotic Strain NTN of Potato Virus Y in Potato

StPIP1, a PAMP-induced peptide in potato, elicits plant defenses and is associated with disease symptom severity in a compatible interaction with potato virus Y

Consequences of Influenza A Virus on Pneumococcal Biofilm Formation and Stability in the Absence of Host Factors

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