Index Catalog // ScholarsArchive@OSU

On the mechanism transition of power transient critical heat flux

Creator:: Yan, Yikuan
Abstract:: The reactivity-initiated accident (RIA) accident has stirred wide interest for the need of designing advanced and high tolerance fuels for next generation nuclear power plants. For pressurized water reactors (PWRs), the accidentally induced reactivity pulse adds transient energy input to the fuel. As a result, boiling may happen locally. Boiling...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Yikuan Yan for the

Effect of Laser Powder Bed Fusion Parameters and Hot Isostatic Pressing on the Microstructure and Mechanical Properties of C22 Alloy

Creator:: Yan, Dongqing
Abstract:: A nickel-based Hastelloy C22 powder with a nominal composition of Ni-21.30Cr-13.36Mo-1.92Co-2.94W-3.85Fe-0.23Mn-0.3V(wt%) and particle size distribution of D₁₀=23.8±0.3 μm, D₅₀=37.5±0.2μm, and D₉₀=59.3±1.1 μm was gas atomized to be used as a feedstock in Laser Powder Bed Fusion (LPBF). In this study, laser power and scanning speed were optimized to manufacture specimens...
Resource Type:: Masters Thesis
Full Text:: THE THESIS OF Dongqing Yan for the degree of Master of Science in Mechanical Engineering presented

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Creator:: McKinney, Madison J.
Abstract:: Cystic fibrosis is an inherited genetic disease caused by a single gene mutation in the CFTR protein. Affecting 70,000 people worldwide, this disease is debilitating to patients, resulting in persistent lung infections and decreased quality of life. Due to the various mutation types, there is not currently a single drug...
Resource Type:: Honors College Thesis
Full Text:: experiments with assistance from myself and Kai Slaughter with western blot analysis, confocal microscopy

Synthetic Lubricant Performance in Enclosed Gearbox Applications at Extreme Temperature

Creator:: Marr, Carter J.
Abstract:: The goal of this paper is to evaluate how synthetic lubricants perform in an enclosed gearbox application when compared with a proven mineral oil. This is in an effort to improve gearbox efficiency with the desired effect of lower emissions from of improved energy output from power generation. Four liquid...
Resource Type:: Masters Thesis
Full Text:: and gear analysis for Manuscript #1. Dr. Karl Haapala assisted with the writing of Manuscript #1. Kai

Application of Density Functional Theory to Exploration of Reactions

Creator:: Feoktistova, Taisiia
Abstract:: My work has focused on using density functional theory to elucidate mechanisms of organocatalytic and transition metal catalyzed reactions by considering competing mechanisms. In each of the three presented studies computational investigation complemented experimental work by predicting stereoselectivity or revealing origins of stereo, regio, or chemoselectivity. A study on the...
Resource Type:: Dissertation

An Agent-Based Simulation for Emergency Warning Dissemination in a Multiplex Social Network

Creator:: Koll, Charles D.
Abstract:: The variety of natural disasters provide different sets of characteristics and properties with unique challenges. One significant difference between hazard types is prewarning lead time, the amount of time individuals have from a potential warning to the disaster occurring. Rapid onset disasters may not provide an official warning about a...
Resource Type:: Masters Thesis

Elucidating the Origins of Trends and Selectivities of Organic Reactions through Computations and Data Analysis Techniques

Creator:: Richardson, H. Camille
Abstract:: In this dissertation, a novel method for analyzing computed transition states (TS) for organic reactions is disclosed. It introduces the use of localization-delocalization matrices as parameters in a linear free energy relationship to determine the transition state interactions responsible for differences in energy between the major and minor TS in...
Resource Type:: Dissertation
Full Text:: , Y. Ding and Y.-X. Ding, Tetrahedron, 2008, 64, 10507. 23. J. Yan, Q. Li, J. A. Boutin, M. P. Renard

Development of Miniature Wire pH Sensors for Real-Time Monitoring of the Streptococcus Mutans Biofilm

Creator:: Wong, Derek C.
Abstract:: The interface between a biofilm and the underlying substrate to which it is attached is challenging to study. Currently, available methods of studying this microenvironment have not been able to record data in real-time over a time period in the range of days. To address this challenge, we report the...
Resource Type:: Honors College Thesis
Full Text:: parts of this project. In particular, the advice of Anh Tuan Nguyen, Christopher Bahro, Dr. Durgasha

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Creator:: Kim, Jeonghwan
Abstract:: Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
Resource Type:: Dissertation

Characterization of Heterostructured Nanocrystalline Metals Processed by High-Pressure Torsion

Creator:: Han, Jae-Kyung
Abstract:: High-pressure torsion (HPT) is an effective severe plastic deformation (SPD) technique to produce bulk nanostructured materials (BNMs). These BNMs often show a combination of exceptional mechanical and physical properties. Processing of single metals and alloys by HPT has been understood that the homogenous microstructures can be achieved throughout the disk...
Resource Type:: Dissertation

ScholarsArchive@OSU

On the mechanism transition of power transient critical heat flux

Effect of Laser Powder Bed Fusion Parameters and Hot Isostatic Pressing on the Microstructure and Mechanical Properties of C22 Alloy

Nucleic Acid Based Therapeutics for Treatment of Cystic Fibrosis

Synthetic Lubricant Performance in Enclosed Gearbox Applications at Extreme Temperature

Application of Density Functional Theory to Exploration of Reactions

An Agent-Based Simulation for Emergency Warning Dissemination in a Multiplex Social Network

Elucidating the Origins of Trends and Selectivities of Organic Reactions through Computations and Data Analysis Techniques

Development of Miniature Wire pH Sensors for Real-Time Monitoring of the Streptococcus Mutans Biofilm

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Characterization of Heterostructured Nanocrystalline Metals Processed by High-Pressure Torsion

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