Studies toward the total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, were conducted and resulted in a route to an advanced intermediate, C4-C32, for this purpose. A key feature of our approach is the stereoselective synthesis of two cis-2,6-disubstituted tetrahydropyrans present in the macrolide portion of...
Two studies investigated the characteristics of high-risk Hispanic parents with young children who were enrolled in a primary prevention home visitation program targeting first birth families. In the first study, more and less acculturated high-risk Hispanic families were compared to high-risk non-Hispanic White families on differences in demographic characteristics, risk...
Historical aerial photos were used to examine the early phase of forest succession after stand replacement disturbance, covering the Coast Ranges Province (CRP) and the western Cascades Province (WCP) of western Oregon. The study consisted of two components: characterizing the pattern of forest succession in western Oregon; analyzing the influence...
Two approaches to the tricyclic core of the furanoeremophilane sesquiterpenoids are described. The first approach entails a projected Diels-Alder/retro Diels-Alder reaction of an acetylenic oxazole 64. Construction of the pivotal aldehyde 67 commenced from ketone 68. The acetyenic moiety was then introduced via a Felkin-Ahn addition of lithiopropyne to aldehyde...
Frozen blueberries were pilot-plant-processed into juice and concentrate by 2 treatments (heat and SO2), and a control. Qualitative, and quantitative anthocyanin and polyphenolic content were monitored after each processing step. Major losses occurred after the initial processing steps. Juice processing by-product contained a substantial amount of anthocyanins and polyphenolics (>42%...
Lasting, effective solutions to nitrogen (N) loss from container nurseries must
address layers of complexity ranging in scale from whole system nursery management
to gene expression. Group-based On-site Active Learning (GOAL) was developed to
aid nursery managers and related stakeholders (e.g. neighbors, policy makers,
regulating agencies, researchers) in developing a...
The increasing occurrence of aluminosilicate caused complications in krafi pulp mills can be attributed to the closing of purge points and the expanded use of contaminated feedstocks and recycled fiber sources. An active purge of aluminum and silicon from the chemical recovery cycle must be undertaken in order to maintain...
When biogeochemical models are applied to large regions, the values of key model parameters are often unknowable. Through field and modeling studies, I examined the potential impact of such uncertainty on estimates of carbon cycling in western Oregon. I found that variation in key leaf traits could be interpreted ecologically,...
Some positive-strand RNA plant viruses possess a transfer RNA-like structure (TLS) at the 3'-terminus of their genomic RNAs. The closest mimicry to tRNA is exhibited by the valylatable TLSs from tymoviruses and furo-like viruses, which are able to interact with key cellular tRNA enzymes: [CTP, ATP]:tRNA nucleotidyltransferase (CCA NTase), valyl-tRNA...
The purpose of this investigation was to describe tenth grade students' views
of the purposes of geometric proof within the context of their learning. Classroom
observations, the curriculum, assessment tools, journal questions, and a
preconceptions questionnaire were used to provide context for the views expressed by
students from a single...