3D vector tomography has been explored and results have been achieved in the last few decades. Among these was a reconstruction formula for the solenoidal part of a vector field from its Doppler transform with sources on a curve. The Doppler transform of a vector field is the line integral...
As modern systems continue to increase in size and complexity, they pose significant safety and risk management challenges. System engineers and much of the government research efforts are focused on understanding the attributes and characteristics that emerge from the interactions of components and subsystems. As a result, the objective of...
Improving the understanding the relations of sustainability behaviors in manufacturing systems and actively engaging with manufacturers (especially SMEs) in sustainability efforts is key to the long-term success of U.S. industry and the natural environment. This study addresses this urgent need by establishing a systemic approach for the design of costing...
Estimating the hydraulic conductivity of earth materials is important for many water resource modeling efforts, including predicting the transport of pollutants in ground water, computing surface runoff for flood control, and computing water budgets. This research implicitly used topography, soil, and climate data to estimate plausible continuous hydraulic conductivity values...
The purpose of this dissertation was to increase understanding of adolescent school counseling groups including a literature review of the quantitative outcome research on group work with adolescents in the schools and a qualitative exploration of the adolescent experience of cohesion in rural school counseling groups. Outcome research on group...
The purpose of the dissertation was to gain an understanding of counselor professional identity and identity development, as well as an understanding of the experiences of doctoral students as they develop their professional identity within a nontraditional (hybrid) counselor education (CE) program. This was accomplished through systematic literature review of...
Many important policy problems entail linkages among multiple economic sectors, and require the use of a general equilibrium economic modeling framework. This economic approach is appropriate when the market for any one good or service is linked to numerous other goods and services, and back to fundamental inputs such as...
The potential for electric energy generation from ocean waves is substantial and much research is being conducted on the conversion process as a renewable, grid-connected, power source. Some of the same attributes that make wave energy harvesting attractive as a grid-connected source also make it attractive as a remote, or...
Subduction zone earthquake and tsunami hazards affect tens of millions worldwide and the recurrence of these disasters can be evaluated with paleoseismic techniques, because earthquake cycles (and their supercycles) typically span many millennia. In these three chapters, I discuss a suite of analyses I use to evaluate the sedimentary record...
The application of lean to new product development (NPD) processes has been claimed to generate positive impact on NPD performance. There are very few empirical studies, however, on how organizations should apply lean practices or on the exact nature of the impact of lean on NPD performance. To further understand...
Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
Paleoclimate archives have revealed abrupt climate events that are superimposed on more gradual climate changes throughout the last glacial and deglacial periods. The underlying causes of such rapid climate changes are still poorly understood, but the strong expression of these events in northern hemisphere records likely points to climatic mechanisms...
Active tectonics of a deformation front constrains the kinematic evolution and structural interaction between the fold-thrust belt and the most-recently accreted foreland basin. At the Himalayan deformation front, the thrust front is blind, characterized by a broad fold (the Suruin-Mastgarh anticline (SMA)), and displays no emergent faults cutting the southern...
In 2004 the National Toxicology Program published an article describing their intent to pursue toxicology testing and risk assessment practices solely reliant on high throughput in vitro datasets and in silico modeling for dose-response assessments. Support and contributions form regulatory agencies and a significant portion of the life sciences community...
There is a knowledge gap concerning the outcomes of early adolescent sexual initiation (ASI). In particular, the influence of early ASI upon adult attachment is unknown. A multiple regression study was conducted to address this knowledge gap. Adult partner/spouse attachment was the criterion variable, and the predictor variables included both...
Nuclear Factor, Erythroid Derived 2, Like 2 (NFE2L2 or Nrf2) is the primary transcription factor in cellular defense against oxidative and xenobiotic stresses in higher eukaryotes. This basic leucine zipper transcription factor regulates over 200 antioxidant, detoxification, and lipid metabolizing genes by binding to the Antioxidant Response Element (ARE; a...
The critically endangered Maui's dolphin (Cephalorhynchus hectori maui) and the endangered Hector's dolphin (C. h. hectori) are endemic to the coastal waters of New Zealand, where their primary threat is fisheries-related mortality. The Maui's dolphin is among the most critically endangered cetaceans in the world, with its remnant population primarily...
Research indicates that enduring interparental conflict before, during, and after divorce has negative effects on children. Parental conflict can be reduced utilizing alternative dispute resolution (ADR) processes such as mediation and collaborative divorce. The purpose of this dissertation was to produce two manuscripts examining the role of the child specialist...
The results presented in this dissertation address a number of questions regarding late Pleistocene and Holocene ice-sheet and climate interactions, spanning disciplines involving paleoclimatology and atmospheric science. These studies use various techniques in geochemistry, climate modeling, and ice-sheet modeling to address ice- sheet response to climate and the attendant interactions...
Geologic CO₂ sequestration is a climate change mitigation strategy that prevents CO₂ emissions to the atmosphere by capturing CO₂ gasses from large point source emissions streams and then pressurizing and pumping the supercritical-state CO₂ into underground geologic storage reservoirs. Once underground, CO₂ is prevented from buoyant migration to the surface...
The release of the IEEE802.15.6 standard has led to increased interest in low-power technologies for wireless body-area-networks (WBANs). The power dissipation, supply voltage, and die area are some of the most important criteria for successful WBAN implementations. Digital-intensive RX architectures can potentially result in sub-1V operation with significant reductions in...
Landslides are a pervasive hazard that can result in substantial damage to properties and loss of life throughout the world. To understand the nature and scope of the hazard, landslide hazard mapping has been an area of intense research by identifying areas most susceptible to landslides in order to mitigate...
Quantifying the mass transport through marine sediments, and the geochemical response to such flow with numerical models has become a common and powerful approach for geochemical data interpretation. In this dissertation, I developed and applied transport-reaction models to unravel complex and interdependent reactions involving carbon, sulfur and silica transformations in...
Boyd and Walter (1975) identified the need to provide supervision for school counselors almost forty years ago. Michelle Obama, the First Lady of the United States (2014), in her address at the American School Counselor Association Conference stated that school counselors needed to be provided with professional development opportunities designed...
The three studies that comprise this dissertation seek to answer significant
questions in paleoclimatology through unconventional applications of ice core
greenhouse gas data. These studies involve different gases and span the interval of time
between the Last Glacial Maximum and the Industrial Revolution, but are united by their
nontraditional use...
Passage of blood through a sorbent device for removal of bacteria and endotoxin by specific binding with immobilized, membrane-active, bactericidal peptides holds promise for treating severe blood infections. Peptide insertion in the target membrane and stable binding is desirable, while membrane disruption and release of degradation products to the circulating...
Dental resin composites are widely used in modern dentistry due to their aesthetic appearance. However, resin based restorations have inferior mechanical properties (fracture is the second reason for restorations replacement) in comparison to alloy based composites and their antimicrobial properties still remain poor, leading to secondary tooth decay development on...
Ethanol production from lignocellulosic feedstock has been under intense scrutiny as a transportation fuel due to its potential to address concerns of increasing energy consumption, limited fossil energy resources, climate changes due to greenhouse gas emissions from fossil fuels, and especially use of non-food biomaterials, which address the biggest limitation...
With the growing popularity of kinesiology at the undergraduate level, one would expect the field to be influential. Kinesiology, however, appears to be in a paradox. The undergraduate popularity is not reflected in the rest of academia, or even the general public, many of whom feel kinesiology is not a...
Reintroduction programs are increasingly being used to save animals from extinction and aid in their recovery. The California Condor (Gymnogyps californianus), one of the most endangered birds in the world, is a remarkable example of how reintroduction programs can help rapidly increase a species' population numbers and range following a...
The stereospecific reagent-controlled homologation (StReCH) of boronic esters with putative lithiooxiranes generated in situ from appropriate precursors via sulfoxide-lithium exchange, tin-lithium exchange, and direct lithiation is described with an emphasis on the first lithiation technique which allows for the regio- and stereo-specific generation of all types of lithiooxirane isomer. Transient...
Electric power needs will only grow over the next decades as more humans ascend from poverty into the middle class. Currently, the majority of electric power is generated by burning fossil fuels. To help mitigate the undesirable effects of burning fossil fuels research is being done to increase the efficiency...
The mechanical performance of composite materials is determined by the mechanical properties of their individual components and the effective load transfer between these components. Binders are commonly used to bond composite components together and to provide effective load transfer between them. In wood-based composites the binder-component load transfer occurs at...
This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Environmental sustainability and economic growth is at the forefront of international policy discussions. There is no question that climate change is happening, but also that countries all around the world aspire to continued economic growth. When it comes to climate change, scientists agree that increased carbon dioxide (CO₂) emissions in...
Emerging infectious diseases impact both human and wildlife populations. Infectious agents, in particular the aquatic fungus Batrachochytrium dendrobatidis (chytrid), have an influential role in driving global amphibian population declines. The emergence of the chytrid fungus has aspects of both geographic spread as well as climate shifts altering environmental conditions and...
Since the discovery of molecular chirality in 1848, this notion has had a substantial impact on medicine, biology, and chemistry. Extensive effort has been directed towards the construction of chiral molecules that contain sp³ hybridized stereogenic centers. In contrast, less effort has been dedicated to molecules that are chiral by...
Sustainable management of the world’s forests is a key component for conserving biodiversity, soil and water resources, mitigating climate change, strengthening economies, and promoting sustainable communities and human well-being, now and in the future. While international cooperation is important, the actual policies and management actions that affect forest conditions and...
Recent climatic warming trends and increases in the frequency and extent of wildfires have prompted much concern regarding the potential for rapid change in the structure and function of forested ecosystems around the world. Episodes of mortality in wildfires and insect outbreaks associated with drought have affected large areas and...
Forest management is rapidly undergoing a transformation from a discipline based on efficient commodity production to one for multiple uses, especially on federally managed land in the United States. This new management paradigm has challenged silviculturists to develop and adapt forest management techniques that can deal with increased demands. Using...
Pacific Northwest and California freshwater resources are key elements in the life history and ecology of Pacific salmon and steelhead listed as threatened or endangered under the Endangered Species Act. Risk to listed Pacific salmonid species can be assessed by evaluating the spatial and temporal co-occurrence of salmonid species at...
The ~1 Myr history of the Purico-Chascon volcanic complex (PCVC) records significant changes in the production and storage of magmas in the crust. At ~1 Ma activity at the PCVC initiated with the eruption of a large 80-100 km³ crystal-rich dacite ignimbrite with restricted whole rock ⁸⁷Sr/⁸⁶Sr isotope ratios between...
Phytophthora cinnamomi is a soilborne pathogen that causes root rot disease of highbush blueberry (Vaccinium corymbosum L.). When new installations of susceptible blueberry cultivars are infected with P. cinnamomi, plants often fail to grow significant new tissue, greatly reducing yields over the life of the planting. Chemical fungicides are available...
Sedimentary records from the North Atlantic, instrumental in the development of modern paleo-geomagnetic concepts, show a highly variable field even during times of constant polarity. Yet, our understanding of how the magnetization is acquired in the sediments is poorly understood. Primary magnetizations preserved in deep-sea sediments are known to be...
A microchannel-based hemodialyzer offers a novel approach to hemodialysis practice and holds many promises for improving dialysis treatment efficiency and quality of life for kidney patients. The hollow fiber hemodialyzer, a conventional dialysis device, has certain limitations including non-uniformity of the dialysate flow path which necessitates the use of a...
Infrastructure systems are a critical component supporting today's modern society. From
power grids to traffic networks, we rely on these systems to perform as intended, despite
the various sources of uncertainty present in their operation. Designing for system
robustness can help mitigate the impact of failures caused by unexpected events....
VCO-based ADCs have recently emerged as attractive alternative to conventional DeltaSigma (ΔΣ) modulator architectures. Few salient features of a VCObased ADC are: 1) the quantization noise is 1st order noise shaped, 2) it is an open loop architecture, and, 3) its implementation is mostly digital in nature. Hence, they are...
As computation power continues to grow, the demand for data transfer bandwidth is also rising. This is reflected in the increasing data-rate of high-speed links. However, the increase in data-rate is sustainable only if the I/O energy efficiency improves as well. This dissertation explores several techniques to enable high-speed links...
The production of hydrogen has been one of the most heavily studied, energy related fields over the past half century, yet few methods are commercially or economically viable and none are currently sustainable. Of those aiming at the sustainable production of hydrogen using renewable resources, perhaps the most widely studied...
Discussions around adapting water management systems to climate change often express the need to increase the flexibility and adaptive capacity of current systems, and to implement robust strategies going forth. While these topics lie at the center of many climate change discussions, transforming adaptation recommendations into tangible tools and information...