1-(2-pyridyl)-3-methyl-3-butene-2-ol was prepared by allowing 2-picolyllithium to react with methacrolein.
In the reaction of picolyllithium with crotonaldehyde, two products 1-(2-pyridyl)-4-methyl-3-butene-2-ol and 1-(2-pyridyl)-4-methyl-2-butene-4-ol were formed.
1-(2-pyridyl)-3-methyl-3-butene-2-ol was subjected to the low
pressure hydrogenation, using methanol as solvent and PtO₂ as catalyst. A red yellow liquid 1-(2-pyridyl)-3-methyl-2-butanol was
obtained. Derivatives of the...