Pentobarbital binding to hemoglobin, evidence of an interaction
between pentobarbital and 2,3-DPG in binding to hemoglobin, and the
effect of altered oxygen dissociation on the outcome of barbiturate
poisoning were studied.
Ultrafiltration and equilibrium dialysis techniques were used to
determine the binding of pentobarbital to solutions of purified
hemoglobin, diluted...