The virion protein patterns of 72 isolates of infectious
hematopoietic necrosis virus (IHNV) were analyzed by sodium dodecyl
sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of S-methionine
labeled virus. This analysis led to the classification of these virus
isolates into 4 or more types. Type 1 virus is characterized by a
nucleocapsid protein...
A two-part study was conducted with three poorly water soluble
drugs (phenylbutazone, tolbutamide, theophylline) to develop two new
drug delivery systems based on physical-chemical approaches.
In the first part, tolbutamide and phenylbutazone were made into
solid dispersions with various excipients using a lyophilization
technique. In vitro dissolution studies of these...