Dithiocarbamates are widely used agricultural pesticides, industrial chemicals and
effluent additives. DTCs and their related compounds have historical and current
relevance in clinical and experimental medicine. DTC developmental toxicity is well
established, but poorly understood. Dithiocarbamates according to the U.S. EPA have a
mechanism of action involving, "the inhibition of...
Lateral heel wedge orthotics are designed to reduce medial tibiofemoral joint loading and pain in patients with knee osteoarthritis (OA). To date, the efficacy of long-term lateral heel wedge orthotics use among OA patients has not been determined. This study evaluated the extent to which lateral heel wedge orthotics reduced...