The quorum sensing regulatory pathway has been extensively studied for its impact on the virulence of Pseudomonas aeruginosa, an opportunistic pathogen that causes acute and chronic infections in immunocompromised individuals such as those suffering from the genetic disorder cystic fibrosis. Part of the quorum sensing pathway that has not been...
Skin is the largest organ in the body that protects the organism from environmental, chemical and physical traumas of each passing day. The protective skin epidermal permeability barrier (EPB) is formed within the exterior layers of the epidermis, which are regularly sloughed off and repopulated by movement of inner cells....
Chitosan is a biopolymer resulting from the deacetylation of chitin, the second most abundant biopolymer in nature. Chitosan has been successfully used in systems to remove metal ions and other pollutants from wastewater. Chitosan has shown promise as a sorbent for radionuclides in some aqueous waste streams.
The sorption of...
Part I: Racemic and asymmetric syntheses of a new substance with prospective antidepressant properties were achieved. In vitro assays with synthetic racemates (±)-25 and (±)-26 suggested that the former is a relatively selective inhibitor of serotonin transporter whereas the latter is a more balanced inhibitor of both serotonin and norepinephrine...
Barley and cereal yellow dwarf viruses (B/CYDV) are a suite of aphid-vectored pathogens that affect diverse host communities, including economically important crops. Coinfection of a single host by multiple strains of B/CYDV can result in elevated virulence, incidence, and transmission rates. We develop a model for a single host, two...
In August of 2011, Jenny Minten came across an old coffin, complete with a skeleton, in the Independent Order of Odd Fellows (IOOF) Scio lodge. After it was determined that the skeleton did not represent a modern forensic case, the remains were donated to the Oregon State University Anthropology Department....
Optimal aging is strongly related to personality factors along with health-behavior habits. Personality has played a key role in understanding the interactions between human behavior and the environment and as a vital predictor in determining health outcomes of individuals. Although previous studies have found links between personality traits and health,...
Oregon's ocean waters are a potential source of wind, wave, and tidal energy; of interest to renewable energy entrepreneurs and to the U.S. government as it seeks to bolster energy security. In order to install technology to capture this energy, however, it may be necessary to mitigate conflict with existing...
This thesis explores the relationship between crime, transportation network connectivity, and engineered facilities built to increase walkability through a case study of twenty-five sites within the city of Spokane, Washington. Using data spanning between 2008 and 2010, the author developed a GIS model representing conditions of the built environment, social...
The Altiplano-Puna Volcanic Complex in the Central Andes is one of the youngest large silicic volcanic fields (LSVFs) in the world, erupting over 13,000 km³ of material during multiple supereruptions from 11 to 1 Ma. Understanding the timescales over which magma is stored in the crust prior to eruption is...