The detection of mammalian FMO’s is important in the understanding of active FMO 2.1 and its role in metabolizing drugs to treat tuberculosis. Refinement of an absolute quantification (AQUA) mass spectrometry method is needed to be able to quantify the different FMO isoforms present in mammalian tissue. We are doing...
Farensoid X Receptor (FXR) is a very flavoring protein for the treatment and prevention of the many conditions related to metabolic syndrome. Our experiment explores the binding activities of FXR when introduced to various natural and synthetic ligands. Currently, an initial assay showing the Stern-Volmer relationship of our date supports...