Ebola virus causes an acute hemorrhagic fever lethal in primates and rodents. The contribution of host immune factors to pathogenesis has yet to be determined and may reveal efficacious targets for potential treatment. In this study, we show that the interleukin (IL)-10 signaling pathway modulates Ebola pathogenesis. IL-10 [superscript -...
For many organisms, the reconstruction of source-sink dynamics is hampered by limited knowledge of the spatial
assemblage of either the source or sink components or lack of information on the strength of the linkage for any source-sink
pair. In the case of marine species with a pelagic dispersal phase, these...