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Filtering by: Date issued sim 2015-05-26 Subject Drug development

Mechanistic Studies and Catalytic Engineering of the Pseudoglycosyltransferase VldE

Creator:

Abuelizz, Hatem A.

Abstract:

This thesis describes an investigation of the molecular basis of the substrate specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a newly discovered group of glycosyltransferase (GT)-like proteins that catalyze the transfer of a pseudosugar to an acceptor molecule via a C-N bond formation. This...

Resource Type:

Dissertation