Recent state and national standards have increased the interest in engineering at the K-12 level. Science standards, in particular, have begun to make the case for including engineering throughout the K-12 scope of study. Despite the increased attention to engineering, the characteristics and uniqueness of the field of engineering are...
Background:
In the SOD1^G93A mutant rat model of amyotrophic lateral sclerosis (ALS), neuronal death and rapid paralysis progression are associated with the emergence of activated aberrant glial cells that proliferate in the degenerating spinal cord. Whether pharmacological downregulation of such aberrant glial cells will decrease motor neuron death and prolong...