Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...
Changes in the global climate and forest management practices have given rise to increasing numbers and severity of wildfires. More than five million acres burned in the United States in 2017, while in Canada 7.4 million acres burned. In particular, an increasing amount of dead woody biomass is a key...
With the incredible technological advancements that have come from the introduction of plastic many problems have arisen. Once plastics were created the value of items once they reached their end of life were lowered. Considering the majority of all plastics created are for packaging with single-use intentions people now dispose...
Metamix is a mixture of botanical compounds that promote healing and prevent infection for burns and diabetic ulcers. In this thesis, metamix was incorporated into 1.75 weight percent gellan gum hydrogels as a drug delivery method for burned skin. The ideal concentration of metamix was 25% by solution volume for...
Sunscreen products are used worldwide to protect the skin from ultraviolet radiation. However, some of the ingredients used in sunscreen products are fatal to coral reefs especially in areas where tourism is a large part of the economy. In this study, we explored a synthetic route to produce 4-deoxygadusol, which...
Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
To determine the best poly-ion layers to be used in encapsulation of pyrrolizidine alkaloid degrading anaerobic microbes, a study was carried out to test three layers on coating ability and ability of the bacteria to grow after being coated. Two positive layers, poly(allylamine hydrochloride) (PAH) and poly-L-lysine, and one negative...
The Corvallis Community Relations (CCR) office has launched an initiative called “I Heart Corvallis” that serves to enhance OSU students’ sense of connection and contribution to the greater Corvallis community. The eponymous “I Heart Corvallis” mobile application serves as a central hub for community events and resources available to students...
Using repositories to store product design information can provide additional and extensive design knowledge to the global design community. Using repository data in the design of new products can be especially impactful for DfX design objectives, such as product sustainability, about which many engineering designers have limited knowledge. Furthermore, repositories...