Human actions are pushing natural systems into states that have no historical precedent. In response, empirical and theoretical researchers are increasingly focused on developing ways to predict the responses of ecological systems to change. However, significant knowledge gaps remain, often leading to “ecological surprises” where observed impacts of global change...
In recent years, SAR ADCs have been shown to acheive faster conversion times and improved power efficiencies due to their simple building blocks that are digital in nature and scale favorably with technology. High resolution ADCs with stringent noise requirement has led to the adoption of hybrid ADC architectures such...
Through this dissertation, the quality of freely available physical activity promotion web articles that lay adults would likely locate online was critically appraised and theoretically analyzed. Three broad categories were considered. They were 1) message consistency with national health guidelines for physical activity; 2) suitability for health-related communication; and 3)...
Platelet activation uses a complex set of pathways to respond to vascular injury during hemostasis. However, thrombosis relies on the same set of pathways. Antiplatelet therapies used to prevent thrombotic events often target the P2Y₁₂ platelet receptor for inhibition but can result in bleeding diathesis or in abnormally high ADP...
Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...