Index Catalog // ScholarsArchive@OSU

Effects of selenium supplementation during different trimesters of pregnancy on non-specific humoral immunity of pregnant beef cows and persistence of antibodies in their newborn calves

Creator:: Thompson-Hernandez, Ian
Abstract:: Immunosuppression during the periparturient period leads to increased susceptibility to infectious diseases in beef cows. Newborn calves rely on passive transfer of antibodies from their mothers at birth for protection against diseases in the first two months of age. It is unknown if supranutritional Se supplementation of cows during pregnancy...
Resource Type:: Honors College Thesis
Full Text:: ). Plates were incubated for 1 h at room temperature. After incubation, plates were washed 3 times in

Characterization of a Transgenic Mouse for Human Cytochrome P450 1B1 (CYP1B1)

Creator:: You, Hyekyoung Hannah
Abstract:: Cytochrome P450 1B1 (Cyp1B1) is a xenobiotic metabolizing enzyme, responsible for polycyclic aromatic hydrocarbon (PAH) oxidative metabolism. CYP1B1 metabolically activates several species of environmentally relevant procarcinogenic PAHs to reactive carcinogens. PAHs are aryl hydrocarbon receptor (AhR) agonists, leading to CYP1B1 upregulation. Though CYP1B1 is highly conserved across species, wild type...
Resource Type:: Honors College Thesis
Full Text:: tr ol W at er c on tr ol H- 1- M 1 H- 1- M 2 H- 1- M 3 H- 2- M 1 H- 2- M 2 H

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

Creator:: Luker, Sabrina R.
Abstract:: In current nanotoxicology research, there is a lack of standardization in reporting of zebrafish exposure media and sonication practices. This lack of standardization in use and reporting methods has made reproducing nanoparticle (NP) toxicity results between labs a common issue. It is important to have a standardized way of reporting...
Resource Type:: Undergraduate Thesis
Full Text:: , & Stone, 2007) TiO2 (Aeroxide P25) Bath bath 6 h (again 30 min before dosing) 35 kHz 10000

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: , RARA, RUNX1, SCL, TCF [21] 2011 H. Kikuchi, F. Kuribayashi, N. Kiwaki et al. GCN5 [22] 2013 J

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: , RARA, RUNX1, SCL, TCF [21] 2011 H. Kikuchi, F. Kuribayashi, N. Kiwaki et al. GCN5 [22] 2013 J

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: . Cancer Lett. 362(2):208–217. doi:10.1016/j.canlet.2015.03.041. Chen H, Pan H, Qian Y, Zhou W, Liu X

Inhibition of α-Amylase and α-Glucosidase by Bioflavonoids

Creator:: Griffith, Anneke M. (Tucker)
Abstract:: Various flavonoid-rich plant extracts have shown efficacy in the treatment of diabetes. Although it is often assumed that dietary flavonoids exert biological antioxidant effects, it is possible that the observed effects work in carbohydrate metabolism. In this study we evaluated the effect of catechins and catechin containing extracts on α-amylase...
Resource Type:: Presentation and Honors College Thesis
Full Text:: traditionally used in South Africa for diabetes." J. Ethnopharm. 124, no. 3 (July 2009): 619-624. Fujita, H

The Inhibition of a-Amylase and a-Glucosidase by Bioflavonoids

Creator:: Griffith, Anneke M.
Abstract:: Various flavonoid-rich plant extracts have shown efficacy in the treatment of diabetes. Although it is often assumed that dietary flavonoids exert biological antioxidant effects, it is possible that the observed effects work in carbohydrate metabolism. In this study we evaluated the effect of catechins and catechin containing extracts on α-amylase...
Resource Type:: Honors College Thesis
Full Text:: traditionally used in South Africa for diabetes." J. Ethnopharm. 124, no. 3 (July 2009): 619-624. Fujita, H

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

Creator:: Dien, Thalia
Abstract:: Background Feline injection-site sarcoma (FISS) is a rare and aggressive tumor associated with vaccines, drug injections, and skin trauma in cats. The understanding of FISS remains limited, posing challenges in its diagnosis, treatment, and prevention. In this study, we analyzed the differential expression of miRNAs and their target genes in...
Resource Type:: Undergraduate Thesis

ScholarsArchive@OSU

Effects of selenium supplementation during different trimesters of pregnancy on non-specific humoral immunity of pregnant beef cows and persistence of antibodies in their newborn calves

Characterization of a Transgenic Mouse for Human Cytochrome P450 1B1 (CYP1B1)

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Inhibition of α-Amylase and α-Glucosidase by Bioflavonoids

The Inhibition of a-Amylase and a-Glucosidase by Bioflavonoids

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

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